Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565761 | 0.86 | PTGDR2 (0.59) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL5016734 | 0.85 | CYP3A4 (0.54) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4009938 | 0.84 | KMT2A (0.49) | PTGDR2KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3480872 | 0.83 | PTGDR2 (0.69) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6921762 | 0.81 | PTGDR2 (0.63) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1531280 | 0.81 | PTGDR2 (0.63) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL15362097 | 0.81 | PTGDR2 (0.63) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6573363 | 0.81 | PTGDR2 (0.66) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10788762 | 0.81 | MEN1 (0.66) | PTGDR2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12800021 | 0.81 | KMT2A (0.45) | PTGDR2KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |