Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 19/20 | 0.46 |
| ▸ | CNR1 | P21554 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621073 | 0.95 | NPC1 (0.55) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL1620915 | 0.92 | NPC1 (0.58) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL1621807 | 0.92 | CNR2 (0.52) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL4016742 | 0.90 | NPC1 (0.42) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL1619580 | 0.89 | CNR2 (0.53) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL4017998 | 0.88 | NPC1 (0.48) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL1620815 | 0.87 | CNR2 (0.55) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL4015488 | 0.86 | NPC1 (0.44) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL775524 | 0.85 | CNR2 (0.62) | NPC1SMN1; SMN2CNR2CNR1 | |
| SCHEMBL1621871 | 0.82 | FLT3 (0.53) | NPC1SMN1; SMN2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |