⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038146 | 1.00 | — | — | |
| Propionic Acid SCHEMBL28330900 | 0.77 | FFAR3 (0.46) | — | |
| SCHEMBL8595406 | 0.72 | — | — | |
| SCHEMBL154955 | 0.72 | — | — | |
| SCHEMBL25880577 | 0.72 | — | — | |
| SCHEMBL19561120 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL2532415 | 0.69 | TDP1 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL17927325 | 0.69 | TDP1 (0.31) | — | |
| Iodide SCHEMBL1835509 | 0.69 | TDP1 (0.31) | — | |
| Bromide SCHEMBL2534871 | 0.69 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227967-B2 | Inhibitor compounds of semicarbazide-sensitive amine oxidases | PROXIMAGEN LIMITED (GB) | 2016-01-05 | — | — | US | claimed |
| US-20130102587-A1 | New Enzyme Inhibitor Compounds | PROXIMAGEN LIMITED (GB) | 2013-04-25 | — | — | US | claimed |
| EP-2547677-A2 | INHIBITORS OF SEMICARABAZIDE - SENSITIVE AMINE OXIDASE | Proximagen Limited (GB) | 2013-01-23 | — | — | EP | claimed |
| WO-2011113798-A2 | NEW ENZYME INHIBITOR COMPOUNDS | PROXIMAGEN LIMITED (GB) | 2011-09-22 | — | — | WO | claimed |
| EP-4236937-A1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093849-A1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| US-11311520-B2 | Substituted dihydroimidazopyridinediones as MKNK1 and MKNK2 inhibitors | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-04-26 | — | — | US | disclosed |
| US-20210085656-A1 | SUBSTITUTED DIHYDROIMIDAZOPYRIDINEDIONES AS MKNK1 AND MKNK2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-03-25 | — | — | US | disclosed |
| EP-3749649-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| US-20190350910-A1 | SUBSTITUTED DIHYDROIMIDAZOPYRIDINEDIONES AS MKNK1 AND MKNK2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-11-21 | — | — | US | disclosed |
| WO-2019154953-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
| EP-2714677-B1 | PYRIDINE-AND PYRAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-08-22 | — | — | EP | disclosed |
| EP-0783482-A1 | CATIONIC TRANSPORT REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010555-A9 | CATIONIC TRANSPORT REAGENTS | — | 1996-06-13 | — | — | WO | disclosed |
| WO-1996010555-A1 | CATIONIC TRANSPORT REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-04-11 | — | — | WO | disclosed |
| US-5468592-A | Hydrazide processing stabilizer | FUJI PHOTO FILM CO. LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0618486-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0421146-A2 | Drying agent for painted surfaces | DURSOL-FABRIK, Otto Durst GmbH & Co. KG (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0362006-A1 | Quinoline derivatives, method for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-04-04 | — | — | EP | disclosed |
| EP-0001753-A1 | Thiophosphoric(phosphonic) acid esters, process for their preparation and use as pesticides | BASF Aktiengesellschaft (DE) | 1979-05-16 | — | — | EP | disclosed |