SCHEMBL401655

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL403310	0.92	PDE5A (0.62)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL403045	0.91	PDE5A (0.71)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL405330	0.90	PDE5A (0.70)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL404543	0.90	PDE5A (0.73)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL405332	0.90	KDM4E (0.65)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL404136	0.88	PDE5A (0.77)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL402452	0.87	PDE5A (0.57)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL405547	0.86	PDE5A (0.81)	PDE5AKDM4ERECQLRNASEH1POLB
	SCHEMBL38105	0.85	PDE5A (1.00)	PDE5AKDM4ERECQLPOLBKMT2A
	SCHEMBL404142	0.85	PDE5A (0.69)	PDE5AKDM4ERECQLRNASEH1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.