SCHEMBL4016965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4019811	0.91	KDR (0.78)	KDRKMT2AMEN1ALDH1A1CYP2C9
	SCHEMBL4021553	0.90	KDR (0.76)	KDRKMT2AMEN1MAPTALDH1A1
	SCHEMBL4016597	0.90	KDR (1.00)	KDRKMT2AALDH1A1CYP2C9PKM
	SCHEMBL4023378	0.88	KDR (0.84)	KDRKMT2AMEN1MAPTALDH1A1
	SCHEMBL4023799	0.87	KDR (0.78)	KDRKMT2AMAPTALDH1A1CYP2C9
	SCHEMBL4015002	0.86	KDR (0.71)	KDRKMT2AMEN1MAPTALDH1A1
	SCHEMBL4018819	0.86	KDR (0.71)	KDRKMT2AMEN1ALDH1A1CYP2C9
	SCHEMBL4023395	0.86	KDR (0.77)	KDRKMT2AMEN1MAPTALDH1A1
	SCHEMBL4019980	0.86	KDR (0.80)	KDRKMT2AMEN1MAPTALDH1A1
	SCHEMBL4355714	0.86	KDR (0.73)	KDRKMT2AMEN1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.