Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | GCK | P35557 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621441 | 0.87 | GCK (0.58) | CNR2CNR1GCKLMNAPOLB | |
| SCHEMBL1621202 | 0.84 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL1619354 | 0.79 | KMT2A (0.52) | CNR2CNR1GCKLMNAPOLB | |
| SCHEMBL1621081 | 0.79 | GCK (0.57) | CNR2CNR1GCKLMNAKMT2A | |
| SCHEMBL1619362 | 0.79 | GCK (0.49) | CNR2CNR1GCKLMNAKMT2A | |
| SCHEMBL1621541 | 0.78 | CNR2 (0.71) | CNR2CNR1LMNAALDH1A1 | |
| SCHEMBL10217207 | 0.78 | GCK (0.59) | CNR2CNR1GCKLMNAKMT2A | |
| SCHEMBL4010121 | 0.75 | CNR2 (0.54) | CNR2CNR1LMNAPOLBKMT2A | |
| SCHEMBL1621098 | 0.74 | HTT (0.51) | CNR2CNR1GCKLMNAPOLB | |
| SCHEMBL4011458 | 0.73 | GCK (0.51) | CNR2CNR1GCKLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |