Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843519 | 0.80 | DPP4 (0.42) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL14000057 | 0.75 | KCNH2 (0.52) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL15084807 | 0.75 | KCNH2 (0.52) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL13221611 | 0.75 | KCNH2 (0.53) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL17874925 | 0.75 | KCNH2 (0.53) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL4017764 | 0.74 | DPP4 (0.52) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL6346898 | 0.74 | KCNH2 (0.47) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL3297927 | 0.74 | KCNH2 (0.47) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL852073 | 0.73 | KCNH2 (0.53) | DPP4FAPDPP8DPP9KCNH2 | |
| SCHEMBL11152918 | 0.72 | KCNH2 (0.57) | DPP4FAPDPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094462-A1 | A CRYSTALLINE SYNTHETIC INTERMEDIATE FOR PYRROLIDIN-3-YL-GLYCYLAMINOALKYLBORONATES | PHENOMIX CORPORATION (US) | 2009-07-30 | — | — | WO | disclosed |