Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL280687 | 1.00 | SCN9A (0.82) | SCN9A | |
| SCHEMBL280870 | 0.92 | SCN9A (0.70) | SCN9A | |
| SCHEMBL280921 | 0.90 | SCN9A (1.00) | SCN9A | |
| SCHEMBL280713 | 0.84 | SCN9A (0.76) | SCN9A | |
| SCHEMBL281015 | 0.84 | SCN9A (0.75) | SCN9A | |
| SCHEMBL280748 | 0.84 | SCN9A (0.75) | SCN9A | |
| SCHEMBL19562373 | 0.83 | SCN9A (0.70) | SCN9A | |
| SCHEMBL280988 | 0.83 | SCN9A (0.70) | SCN9A | |
| SCHEMBL19562377 | 0.82 | SCN9A (0.72) | SCN9A | |
| SCHEMBL328323 | 0.82 | SCN9A (0.69) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073806-A2 | USE OF SPIRO-OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008060789-A2 | USE OF SPIRO-OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-05-22 | — | — | WO | disclosed |