Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 7/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016414 | 0.95 | PAK1 (0.63) | PAK1KDRAURKAMETTEK | |
| SCHEMBL4025750 | 0.93 | PAK1 (0.66) | PAK1CNR1P2RX7MEN1KMT2A | |
| SCHEMBL4021559 | 0.88 | KDR (0.51) | PAK1KDRAURKAMETTEK | |
| SCHEMBL4023766 | 0.86 | PAK1 (0.66) | PAK1PDGFRBCNR1MALT1P2RX7 | |
| SCHEMBL4024568 | 0.84 | PAK1 (0.68) | PAK1PDGFRBCNR1MALT1P2RX7 | |
| SCHEMBL4023555 | 0.84 | PAK1 (0.52) | PAK1PDGFRBCNR1MALT1P2RX7 | |
| SCHEMBL4583078 | 0.82 | KDR (0.56) | PAK1KDRAURKAMETTEK | |
| SCHEMBL4020785 | 0.82 | PAK1 (0.66) | PAK1CNR1MALT1P2RX7MEN1 | |
| SCHEMBL4024515 | 0.82 | PAK1 (0.56) | PAK1KDRAURKAMETTEK | |
| SCHEMBL4581785 | 0.82 | PAK1 (0.63) | PAK1CNR1P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |