Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 20/20 | 0.79 |
| ▸ | NR1H3 | Q13133 | 20/20 | 0.79 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010672 | 0.94 | NR1H2 (0.72) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4011428 | 0.89 | NR1H2 (0.85) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4013026 | 0.88 | NR1H2 (1.00) | NR1H2NR1H3PPARG | |
| SCHEMBL4011541 | 0.87 | NR1H2 (0.73) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4010889 | 0.87 | NR1H2 (0.81) | NR1H2NR1H3PPARG | |
| SCHEMBL4014666 | 0.87 | NR1H2 (0.76) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4009746 | 0.87 | NR1H2 (0.84) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4018299 | 0.87 | NR1H2 (0.84) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4011729 | 0.87 | NR1H3 (0.78) | NR1H2NR1H3 | |
| SCHEMBL4012158 | 0.86 | NR1H2 (0.82) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | claimed |