Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16057132 | 1.00 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6940829 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6934840 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5224444 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6936495 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6933555 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6934123 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6936448 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9625811 | 0.91 | HTT (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5222263 | 0.88 | MEN1 (0.48) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090063-A1 | STEROID SAPOGENIN, ANDROSTANE AND TRITERPENOID SAPOGENIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF INFECTIOUS DISEASES | JADO TECHNOLOGIES GMBH (DE) | 2009-07-23 | — | — | WO | disclosed |