SCHEMBL4019331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4015002	0.91	KDR (0.71)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4021297	0.89	KDR (0.53)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4016924	0.88	KDR (0.67)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4016715	0.88	KDR (0.79)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL1942515	0.88	KDR (0.53)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4018128	0.88	KDR (0.58)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4023772	0.87	KDR (0.66)	KDRKMT2ASMN1; SMN2TP53PKM
	SCHEMBL4019414	0.87	KDR (0.71)	KDRKMT2ASMN1; SMN2TP53NAMPT
	SCHEMBL4022615	0.87	KDR (0.68)	KDRKMT2ASMN1; SMN2TP53FLT1
	SCHEMBL4019811	0.87	KDR (0.78)	KDRKMT2ASMN1; SMN2FLT1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.