Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693207 | 1.00 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL3015031 | 1.00 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL1439307 | 1.00 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL30178687 | 0.86 | — | — | |
| SCHEMBL25603324 | 0.83 | — | — | |
| SCHEMBL30178600 | 0.83 | — | — | |
| SCHEMBL25603320 | 0.83 | — | — | |
| SCHEMBL25603329 | 0.83 | — | — | |
| SCHEMBL17688660 | 0.82 | — | — | |
| SCHEMBL17688598 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |