Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023410 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL4021980 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL16465771 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL4023411 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL6869502 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL4021971 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL4020177 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL6869509 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL2067947 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5TERTMAPTBLM | |
| SCHEMBL4017990 | 0.95 | KDM4E (0.64) | EPHX2HSD17B10FABP4LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476756-B2 | Alkyl-, alkenyl- and alkynylcarbamate derivatives, their preparation and their application in therapeutics | SANOFI-AVENTIS (FR) | 2009-01-13 | — | — | US | disclosed |
| US-20080103197-A1 | ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103197-A1 | ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ALK, ALKBH3, IDH1 | EPHX2 706/4885SLC6A5 3733/4885TERT 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.