Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291848 | 1.00 | AR (0.77) | ARHDAC1PGR | |
| SCHEMBL2693558 | 0.94 | AR (0.81) | ARHDAC1PGR | |
| SCHEMBL1714908 | 0.93 | AR (0.82) | ARHDAC1PGR | |
| SCHEMBL29453440 | 0.93 | AR (0.82) | ARHDAC1PGR | |
| SCHEMBL3868030 | 0.92 | AR (0.80) | ARHDAC1PGR | |
| SCHEMBL8517259 | 0.92 | AR (0.80) | ARHDAC1PGR | |
| SCHEMBL13647000 | 0.92 | AR (0.74) | ARHDAC1PGR | |
| SCHEMBL4024956 | 0.91 | AR (0.77) | ARHDAC1 | |
| SCHEMBL8704637 | 0.91 | AR (0.77) | ARHDAC1 | |
| SCHEMBL8516863 | 0.90 | AR (0.79) | ARHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580459-B1 | Substituted Phenylimidazolidins, their use as medicaments and their pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2001-03-28 | — | — | EP | claimed |
| US-RE35956-E | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1998-11-10 | — | — | US | claimed |
| US-5627201-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1997-05-06 | — | — | US | claimed |
| EP-0494819-B1 | Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1996-07-10 | — | — | EP | claimed |
| US-5411981-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1995-05-02 | — | — | US | claimed |
| EP-0580459-A1 | Substituted Phenylimidazolidins, process for their preparation, their use as medicaments and their pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1994-01-26 | — | — | EP | claimed |
| EP-0494819-A1 | Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-07-15 | — | — | EP | claimed |
| JP-6073017-A | — | — | None | — | — | JP | disclosed |
| WO-2009097996-A1 | USE OF SUBSTITUTED PHENYLIMIDAZOLIDINES FOR PRODUCING MEDICAMENTS FOR TREATING METABOLIC SYNDROME | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
| EP-1622894-B1 | ANTITUMORAL ANTIANDROGENIC PYRROLIDINES | BAYER SCHERING PHARMA AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-0671156-B1 | Process to prepare cosmetic or pharmaceutical compositions containing liposomes | AVENTIS PHARMA SA (FR) | 2001-10-24 | — | — | EP | disclosed |
| EP-0580459-B1 | Substituted Phenylimidazolidins, their use as medicaments and their pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2001-03-28 | — | — | EP | disclosed |
| US-6162444-A | Cosmetic or pharmaceutical compositions | HOECHST MARION ROUSSEL (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5627201-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1997-05-06 | — | — | US | disclosed |
| EP-0494819-B1 | Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1996-07-10 | — | — | EP | disclosed |
| EP-0671156-A1 | Cosmetic or pharmaceutical compositions containing liposomes | ROUSSEL UCLAF (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5411981-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1995-05-02 | — | — | US | disclosed |
| JP-H0673017-A | NEW SUBSTITUTED PHENYLIMIDAZOLIDINE, ITS PREPARATION, ITS USE AS MEDICINE AND PHARMACEUTICAL COMPOSITION CONTAINING IT | ROUSSEL UCLAF | 1994-03-15 | — | — | JP | disclosed |
| EP-0580459-A1 | Substituted Phenylimidazolidins, process for their preparation, their use as medicaments and their pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1994-01-26 | — | — | EP | disclosed |
| EP-0494819-A1 | Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-07-15 | — | — | EP | disclosed |