Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556113 | 0.89 | DPP4 (0.88) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556105 | 0.89 | DPP4 (0.88) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556791 | 0.88 | DPP4 (0.75) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555632 | 0.86 | DPP4 (0.77) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555212 | 0.86 | DPP4 (0.77) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556506 | 0.84 | DPP4 (0.82) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555522 | 0.83 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555869 | 0.83 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555920 | 0.83 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL14392635 | 0.83 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560450-B2 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2009-07-14 | — | — | US | disclosed |
| EP-1565468-A1 | NOVEL XANTHIN DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046148-A1 | NOVEL XANTHIN DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-03 | — | — | WO | disclosed |