Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872215 | 0.79 | IDO1 (0.61) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28287055 | 0.79 | IDO1 (0.66) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4020894 | 0.76 | CYP3A4 (0.56) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9530614 | 0.76 | IDO1 (0.48) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11073181 | 0.73 | CYP3A4 (0.54) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16487324 | 0.73 | CYP3A4 (0.64) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4020891 | 0.72 | CYP3A4 (0.55) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5855482 | 0.71 | CYP3A4 (0.67) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16382293 | 0.70 | IDO1 (0.73) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31408101 | 0.70 | IDO1 (0.73) | CYP1A2CYP2C19CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046756-A2 | PREPARATION OF TELMISARTAN SALTS | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-04-15 | — | — | EP | disclosed |
| WO-2007147889-A2 | PREPARATION OF TELMISARTAN SALTS | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2007-12-27 | — | — | WO | disclosed |