Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.56 |
| ▸ | KDR | P35968 | 11/20 | 0.55 |
| ▸ | CSK | P41240 | 3/20 | 0.55 |
| ▸ | TEK | Q02763 | 3/20 | 0.55 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023215 | 1.00 | SRC (0.56) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4027646 | 0.90 | SRC (0.69) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4021611 | 0.89 | SRC (0.54) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4026483 | 0.88 | SRC (0.58) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4559273 | 0.88 | SRC (0.58) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4025613 | 0.87 | SRC (0.56) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4023374 | 0.87 | KDR (0.55) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4023066 | 0.84 | SRC (0.52) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4023490 | 0.84 | SRC (0.62) | SRCKDRCSKTEKEPHB4 | |
| SCHEMBL4023498 | 0.84 | SRC (0.62) | SRCKDRCSKTEKEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1528925-B1 | QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2009-04-22 | — | — | EP | claimed |