Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.53 |
| ▸ | GRM5 | P41594 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728908 | 0.82 | NPY5R (0.55) | NPY5RGRM5 | |
| SCHEMBL3738915 | 0.82 | NPY5R (0.55) | NPY5RGRM5 | |
| SCHEMBL3738918 | 0.82 | NPY5R (0.55) | NPY5RGRM5 | |
| SCHEMBL13079376 | 0.82 | GRM5 (0.62) | NPY5RGRM5 | |
| SCHEMBL3741651 | 0.81 | NPY5R (0.61) | NPY5RGRM5 | |
| SCHEMBL4020135 | 0.81 | NPY5R (0.61) | NPY5RGRM5 | |
| SCHEMBL3754556 | 0.81 | NPY5R (0.54) | NPY5RGRM5OPRM1OPRL1 | |
| SCHEMBL3741649 | 0.81 | NPY5R (0.61) | NPY5RGRM5 | |
| SCHEMBL4020139 | 0.81 | NPY5R (0.61) | NPY5RGRM5 | |
| SCHEMBL3004620 | 0.81 | NPY5R (0.54) | NPY5RGRM5OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095377-A1 | SPIRO COMPOUNDS AS NPY Y5 RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-08-06 | — | — | WO | claimed |