Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 12/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028387 | 0.87 | SCARB1 (0.61) | SCARB1HSD17B10NPC1ACLYPTGDR2 | |
| SCHEMBL13746689 | 0.86 | SCARB1 (0.72) | SCARB1HSD17B10 | |
| SCHEMBL13746722 | 0.83 | SCARB1 (0.65) | SCARB1HSD17B10NPC1PTGDR2RORC | |
| SCHEMBL4024472 | 0.82 | SCARB1 (0.68) | SCARB1HSD17B10NPC1PTGDR2KDM4E | |
| SCHEMBL4192941 | 0.81 | SCARB1 (0.66) | SCARB1HSD17B10NPC1PTGDR2RORC | |
| SCHEMBL4192256 | 0.81 | SCARB1 (0.72) | SCARB1HSD17B10NPC1PTGDR2RORC | |
| SCHEMBL4195549 | 0.81 | SCARB1 (0.68) | SCARB1HSD17B10NPC1PTGDR2KDM4E | |
| SCHEMBL4028758 | 0.80 | SCARB1 (0.72) | SCARB1HSD17B10NPC1PTGDR2RORC | |
| SCHEMBL4023805 | 0.79 | SCARB1 (0.61) | SCARB1HSD17B10NPC1ACLYPTGDR2 | |
| SCHEMBL4030252 | 0.79 | SCARB1 (0.70) | SCARB1HSD17B10NPC1PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |