Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022924 | 1.00 | HDAC8 (0.47) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL6977604 | 0.79 | HDAC8 (0.52) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL26781562 | 0.77 | PDCD1LG2 (0.35) | ENPEPMMECA1CA2 | |
| SCHEMBL15475245 | 0.77 | HDAC8 (0.58) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL31057050 | 0.76 | HDAC8 (0.52) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL26263797 | 0.75 | DPP4 (0.47) | ENPEPMME | |
| SCHEMBL30684497 | 0.75 | DPP4 (0.47) | ENPEPMME | |
| SCHEMBL3355578 | 0.74 | HDAC8 (0.50) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL27427799 | 0.74 | HDAC8 (0.46) | HDAC8HDAC7HDAC6HDAC9HDAC5 | |
| SCHEMBL4021260 | 0.74 | HDAC8 (0.46) | HDAC8HDAC7HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106379-C | 2-propylvaleramide and 2-propylpentenamide derivatives and their use as anticonvulsants | YISSUM RES DEV CO (IL) | 2003-04-23 | — | — | CN | claimed |
| CN-1111907-A | 2-propylvaleramide and 2-propylpentenamide derivatives and their use as anticonvulsants | YISSUM RES DEV CO (IL) | 1995-11-15 | — | — | CN | claimed |
| EP-1626707-A4 | SUSTAINED RELEASE FORMULATION OF N-(2-PROPYLPENTANOYL) GLYCINAMIDE AND RELATED COMPOUNDS | YISSUM RES DEV CO (IL) | 2009-07-01 | — | — | EP | disclosed |
| CN-100457720-C | 2-propyl valeramide and 2-propyl pentaenuylamide derivative and application used as anti-convulsion medicine | YISSUM RES DEV CO (IL) | 2009-02-04 | — | — | CN | disclosed |
| EP-1626707-A2 | SUSTAINED RELEASE FORMULATION OF N-(2-PROPYLPENTANOYL) GLYCINAMIDE AND RELATED COMPOUNDS | Teva Pharmaceutical Industries Limited (IL) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004071421-A2 | SUSTAINED RELEASE FORMULATION OF N-(2-PROPYLPENTANOYL) GLYCINAMIDE AND RELATED COMPOUNDS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-08-26 | — | — | WO | disclosed |
| CN-1418869-A | 2-propyl valeramide and 2-propyl pentaenuylamide derivative and application used as anti-convulsion medicine | YISSUN RES DEV CO OF THE HEBRE (IL) | 2003-05-21 | — | — | CN | disclosed |
| CN-1106379-C | 2-propylvaleramide and 2-propylpentenamide derivatives and their use as anticonvulsants | YISSUM RES DEV CO (IL) | 2003-04-23 | — | — | CN | disclosed |
| CN-1111907-A | 2-propylvaleramide and 2-propylpentenamide derivatives and their use as anticonvulsants | YISSUM RES DEV CO (IL) | 1995-11-15 | — | — | CN | disclosed |