Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620267 | 0.94 | EPHX1 (0.48) | EPHX1HDAC1HDAC3HDAC2ALOX15 | |
| SCHEMBL4072926 | 0.87 | EPHX1 (0.56) | EPHX1HDAC1HDAC3HDAC2CASP2 | |
| SCHEMBL7113513 | 0.85 | EPHX1 (0.68) | EPHX1CASP2 | |
| SCHEMBL10749585 | 0.85 | — | — | |
| SCHEMBL8242454 | 0.83 | EPHX1 (0.72) | EPHX1CASP2 | |
| SCHEMBL1395514 | 0.83 | EPHX1 (0.71) | EPHX1CASP2DPP7 | |
| SCHEMBL18641844 | 0.81 | EPHX1 (0.75) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL7749273 | 0.81 | EPHX1 (0.75) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL7749192 | 0.81 | EPHX1 (0.75) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL9811711 | 0.81 | EPHX1 (0.75) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128348-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Remicine IP B.V. (NL) | 2023-04-27 | — | — | US | claimed |
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| EP-4125843-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Nomoreitis B.V. (BE) | 2023-02-08 | — | — | EP | claimed |
| CN-115605194-A | Treatment of excessive inflammatory syndrome | 诺莫雷蒂斯私人有限公司（BE） | 2023-01-13 | — | — | CN | claimed |
| CN-113817000-A | Ferrocene-triazole Schiff base derivative and preparation method thereof | 哈尔滨理工大学 | 2021-12-21 | — | — | CN | claimed |
| WO-2021201680-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | HASAN DJOHAN (BE) | 2021-10-07 | — | — | WO | claimed |
| WO-2009023357-A2 | CURCUMIN DERIVATIVES AND THEIR USE AS RADIOPROTECTORS | UNIVERSITY OF ROCHESTER (US) | 2009-02-19 | — | — | WO | claimed |
| EP-0713130-B1 | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORP (US) | 1998-02-11 | — | — | EP | claimed |
| EP-0713130-A2 | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORPORATION (US) | 1996-05-22 | — | — | EP | claimed |
| US-5439776-A | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORPORATION (US) | 1995-08-08 | — | — | US | claimed |
| CN-115819414-B | N-acyl-containing aryl hydrazone derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-28 | — | — | CN | disclosed |
| US-20230128348-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Remicine IP B.V. (NL) | 2023-04-27 | — | — | US | disclosed |
| CN-115819414-A | N-acyl-containing aryl hydrazone derivatives, and preparation method and application thereof | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |
| EP-4125843-A1 | TREATMENT OF HYPERINFLAMMATORY SYNDROME | Nomoreitis B.V. (BE) | 2023-02-08 | — | — | EP | disclosed |
| CN-115605194-A | Treatment of excessive inflammatory syndrome | 诺莫雷蒂斯私人有限公司（BE） | 2023-01-13 | — | — | CN | disclosed |
| WO-2002014321-A9 | USE OF STAT-6 INHIBITORS AS THERAPEUTIC AGENTS | UNIV CALIFORNIA (US) | 2003-03-27 | — | — | WO | disclosed |
| WO-2002014321-A1 | USE OF STAT-6 INHIBITORS AS THERAPEUTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-02-21 | — | — | WO | disclosed |
| EP-0713130-B1 | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORP (US) | 1998-02-11 | — | — | EP | disclosed |
| EP-0713130-A2 | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5439776-A | Isothiouronium salts as photographic nucleating agents | SUN CHEMICAL CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |