Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225736 | 0.98 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3225730 | 0.98 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3222157 | 0.76 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3222160 | 0.76 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3222167 | 0.76 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3222144 | 0.76 | CHRM2 (0.50) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3207101 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3207097 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3211732 | 0.72 | CHRM2 (0.51) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3211749 | 0.72 | CHRM2 (0.51) | CHRM2CHRM1MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098453-A1 | AZONIA BICYCLOALKANES AS M3 MUSCARINIC ACETYLCHOLIN RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |