SCHEMBL4024294

SCHEMBL4024294

CC(C)(C)NC(=O)c1cc2c(-c3ccc(Cl)cc3)n(-c3ccc(Cl)cc3Cl)nc2[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.49
CNR1 P21554 6/20 0.48
PPARA Q07869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4178355 0.86 CNR2 (0.49) CNR2CNR1PPARA
SCHEMBL13746574 0.86 CNR2 (0.48) CNR2CNR1PPARA
SCHEMBL13745965 0.82 CNR2 (0.48) CNR2CNR1
SCHEMBL4023475 0.82 CNR1 (0.53) CNR2CNR1PPARA
SCHEMBL4020983 0.82 CNR2 (0.53) CNR2CNR1
SCHEMBL4026403 0.79 CNR2 (0.48) CNR2CNR1
SCHEMBL4911784 0.71 CNR1 (0.72) CNR2CNR1
SCHEMBL4022535 0.71 CNR1 (0.43) CNR1
SCHEMBL25240037 0.71 CNR2 (0.68) CNR2CNR1
SCHEMBL13745892 0.71 CNR2 (0.52) CNR2CNR1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009095752-A1 FUSED PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS GLENMARK PHARMACEUTICALS, S.A. (US) 2009-08-06 WO disclosed