Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695022 | 0.97 | AR (0.64) | ARPGRHDAC1 | |
| SCHEMBL4023010 | 0.93 | AR (0.60) | ARPGRHDAC1 | |
| SCHEMBL4025013 | 0.91 | AR (0.61) | ARPGRHDAC1 | |
| SCHEMBL29453440 | 0.88 | AR (0.82) | ARPGRHDAC1 | |
| SCHEMBL1714908 | 0.88 | AR (0.82) | ARPGRHDAC1 | |
| SCHEMBL9007822 | 0.88 | AR (0.60) | ARHDAC1 | |
| SCHEMBL4025434 | 0.88 | AR (0.60) | ARHDAC1 | |
| SCHEMBL8517259 | 0.87 | AR (0.80) | ARPGRHDAC1 | |
| SCHEMBL3868030 | 0.87 | AR (0.80) | ARPGRHDAC1 | |
| SCHEMBL4025731 | 0.86 | AR (0.58) | ARHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097996-A1 | USE OF SUBSTITUTED PHENYLIMIDAZOLIDINES FOR PRODUCING MEDICAMENTS FOR TREATING METABOLIC SYNDROME | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
| EP-0671156-B1 | Process to prepare cosmetic or pharmaceutical compositions containing liposomes | AVENTIS PHARMA SA (FR) | 2001-10-24 | — | — | EP | disclosed |
| EP-0580459-B1 | Substituted Phenylimidazolidins, their use as medicaments and their pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2001-03-28 | — | — | EP | disclosed |
| US-6162444-A | Cosmetic or pharmaceutical compositions | HOECHST MARION ROUSSEL (FR) | 2000-12-19 | — | — | US | disclosed |
| US-RE35956-E | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1998-11-10 | — | — | US | disclosed |
| US-5627201-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1997-05-06 | — | — | US | disclosed |
| EP-0671156-A1 | Cosmetic or pharmaceutical compositions containing liposomes | ROUSSEL UCLAF (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5411981-A | Phenylimidazolidines having antiandrogenic activity | ROUSSEL UCLAF (FR) | 1995-05-02 | — | — | US | disclosed |
| EP-0580459-A1 | Substituted Phenylimidazolidins, process for their preparation, their use as medicaments and their pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1994-01-26 | — | — | EP | disclosed |