Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020966 | 0.89 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4026493 | 0.89 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4193787 | 0.88 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4202088 | 0.88 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4020046 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4192559 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4021411 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4018816 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL4024299 | 0.87 | HRH3 (1.00) | HRH3CYP2D6 | |
| SCHEMBL29761952 | 0.86 | NPSR1 (0.90) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095394-A1 | DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2009-08-06 | — | — | WO | claimed |
| WO-2009095394-A1 | DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2009-08-06 | — | — | WO | disclosed |