Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034962 | 0.89 | HRH3 (0.61) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2886931 | 0.85 | SLC6A4 (0.64) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2885799 | 0.84 | SLC6A4 (0.79) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2890115 | 0.80 | HRH3 (0.56) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2886041 | 0.72 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2887980 | 0.72 | SLC6A4 (0.74) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2881601 | 0.69 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2886850 | 0.69 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2886856 | 0.69 | SLC6A4 (0.80) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2887495 | 0.68 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049466-A1 | BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008002817-A1 | BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | WO | claimed |