Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 19/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 19/20 | 1.00 |
| ▸ | CDK2 | P24941 | 19/20 | 1.00 |
| ▸ | CDK4 | P11802 | 9/20 | 0.65 |
| ▸ | CCND1 | P24385 | 9/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025155 | 0.85 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4026037 | 0.84 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4025529 | 0.83 | CCNE2 (0.83) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4030479 | 0.81 | CCNE2 (0.83) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4027353 | 0.81 | CCNE2 (0.83) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4028714 | 0.81 | CCNE2 (0.67) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4026934 | 0.80 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4025522 | 0.79 | CCNE2 (0.71) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4023665 | 0.79 | CCNE2 (0.69) | CCNE2CCNE1CDK2CDK4CCND1 | |
| SCHEMBL4025763 | 0.79 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071668-B1 | 5-AMINOINDENO[1,2-C]PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2009-06-03 | — | — | EP | claimed |
| EP-1071668-B1 | 5-AMINOINDENO[1,2-C]PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2009-06-03 | — | — | EP | disclosed |