Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 9/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 7/20 | 1.00 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.78 |
| ▸ | GSK3A | P49840 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024980 | 1.00 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL14063548 | 1.00 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116909 | 0.94 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116047 | 0.94 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2116045 | 0.94 | GSK3B (0.89) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| Hydrochloric Acid SCHEMBL2119087 | 0.93 | GSK3B (0.87) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13910887 | 0.93 | GSK3B (0.86) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13910604 | 0.93 | GSK3B (0.90) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL13910353 | 0.92 | GSK3B (0.85) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL2118939 | 0.91 | GSK3B (0.84) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100488958-C | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP SANOFI (JP) | 2009-05-20 | — | — | CN | claimed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | claimed |
| US-20050090490-A1 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-04-28 | — | — | US | claimed |
| CN-1556804-A | 3-substituted-4-pyrimidone derivatives | ������ҩ��ʽ���� | 2004-12-22 | — | — | CN | claimed |
| CN-1810802-B | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP | 2011-04-27 | — | — | CN | disclosed |
| CN-100488958-C | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP SANOFI (JP) | 2009-05-20 | — | — | CN | disclosed |
| EP-1427720-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | EP | disclosed |
| EP-1427720-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | EP | disclosed |
| CN-101274928-A | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP (JP) | 2008-10-01 | — | — | CN | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| CN-1810802-A | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP (JP) | 2006-08-02 | — | — | CN | disclosed |
| US-20050090490-A1 | 3-Substituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-04-28 | — | — | US | disclosed |
| CN-1556804-A | 3-substituted-4-pyrimidone derivatives | ������ҩ��ʽ���� | 2004-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090490-A1 | 3-Substituted-4-pyrimidone derivatives | CDK1, TTBK1, CDK2 | GSK3B 247/4885CYP2D6 1144/4885CYP1A2 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.