Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.62 |
| ▸ | PPARA | Q07869 | 15/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032215 | 0.90 | PPARG (0.57) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4028741 | 0.89 | PPARG (0.79) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4028579 | 0.88 | PPARA (0.78) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4028955 | 0.88 | PPARA (0.78) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4027730 | 0.86 | PPARG (0.56) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4028587 | 0.85 | PPARA (0.55) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4029552 | 0.85 | PPARG (0.68) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4032672 | 0.85 | PPARA (0.79) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4026126 | 0.84 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL4032975 | 0.84 | PPARA (0.56) | PPARGPPARAFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |