Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 7/20 | 0.70 |
| ▸ | CA12 | O43570 | 6/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.57 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.57 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027171 | 1.00 | CA9 (0.70) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL4025830 | 0.89 | CA12 (0.57) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL4027170 | 0.89 | CA12 (0.57) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL9697407 | 0.88 | HDAC1 (0.72) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL9697341 | 0.88 | HDAC1 (0.72) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL9697335 | 0.86 | HDAC1 (0.70) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL9696765 | 0.86 | HDAC1 (0.70) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL9695737 | 0.83 | CA9 (0.64) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL13566544 | 0.82 | HDAC1 (0.55) | CA9CA12CA2HDAC1HDAC2 | |
| SCHEMBL3941396 | 0.82 | HDAC1 (0.74) | CA9CA12CA2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312377-A1 | DERIVATIVES OF BENZO[D]ISOTHIAZOLES AS HISTONES DEACETYLASE INHIBITORS | UNIVERSIDAD DE GRANADA (ES) | 2009-12-17 | — | — | US | disclosed |
| EP-2045246-A1 | DERIVATIVES OF BENZO[D] ISOTHIAZOLES AS HISTONE DEACETYLASE INHIBITORS | Universidad De Granada (ES) | 2009-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312377-A1 | DERIVATIVES OF BENZO[D]ISOTHIAZOLES AS HISTONES DEACETYLASE INHIBITORS | HDAC1, HDAC2, HDAC3 | CA9 1485/4885CA12 3053/4885CA2 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.