SCHEMBL402583

SCHEMBL402583

Cc1noc(N)c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28751278 0.97
SCHEMBL3625476 0.78
SCHEMBL5154815 0.77
SCHEMBL23534073 0.75 ACACB (0.33)
SCHEMBL4632027 0.72
SCHEMBL8040682 0.72
SCHEMBL12486 0.69
SCHEMBL3269962 0.69
SCHEMBL24191100 0.69 BRD4 (0.39)
SCHEMBL573503 0.69 NPC1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118930532-A Preparation method of kidney disease treatment medicine 北京康立生医药技术开发有限公司 2024-11-12 CN claimed
CN-106188115-A Cheap highly effective synthesizes the new method of 2 borono N diformazan isoxazolyl N methoxy (ethoxy) methyl benzenesulfonamides 北京理工大学 2016-12-07 CN claimed
CN-102603655-A Synthetic method of deuterium-marked sulfanilamide SHANGHAI RES INST CHEMICAL IND 2012-07-25 CN claimed
US-7683097-B2 Topoisomerase inhibitors Propharmacon Inc. (US) 2010-03-23 US claimed
US-20100010035-A1 Novel Dual Action Receptors Antagonists (Dara) at the Ati and Eta Receptors TORRENT PHARMACEUTICALS LTD. (IN) 2010-01-14 US claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
US-7365056-B2 Substituted 9a-N-(N′-(sulfonyl)phenylcarbamoyl)derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithomycin A and 5-0-desosaminyl-9-deoxo-9-dihydro-9-a-aza-9a-homoerithronolide A GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O (HR) 2008-04-29 US claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
EP-1575969-B1 SUBSTITUTED 9a-N-(N'- 4-(SULFONYL)PHENYL CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DI-HYDRO-9A-AZA-9A-HOMOERITHRONOLIDE A PLIVA ISTRAZIVACKI INST D D O (HR) 2006-07-12 EP claimed
US-20060084795-A1 Substituted 9a-n-[n'-(benzenesulfonyl)carbamoyl-aminopropyl]and 9a-n-[n'-(b-cya-neothyl) -n-[n'-(benzenesulfonyl)carbamoyl-y-aminopropyl]derivatives of 9-deoxo-9-dihydro-9a-aza- 9a-homoerithromycin a and 5-0-aza-homoerithronolide a PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) 2006-04-20 US claimed
WO-2004043985-A1 SUBSTITUTED 9A-N-{N'-[4-(SULFONYL)PHENYL]CARBAMOYL} DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9A-AZA-9A-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL­-9-DEOXO-9-DI-HYDRO-9A-AZA-9A-HOMOERITHRONOLIDE A PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (HR) 2004-05-27 WO claimed
WO-2004037248-A2 MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY CAREX SA (FR) 2004-05-06 WO claimed
EP-1325006-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR NEUROGEN CORPORATION (US) 2003-07-09 EP claimed
US-20030105081-A1 Heterocyclic compounds as ligands of the GABAA receptor PFIZER INC 2003-06-05 US claimed
WO-2002012442-A2 HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR NEUROGEN CORPORATION (US) 2002-02-14 WO claimed
EP-0904077-A4 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL MYERS SQUIBB CO (US) 1999-12-22 EP claimed
EP-0904077-A2 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-31 EP claimed
EP-0500616-B1 OLIGOMERIC TO POLYMERIC CHARACTER COMPLEXES ATOTECH DEUTSCHLAND GMBH (DE) 1998-01-07 EP claimed
WO-1997029747-A1 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1997-08-21 WO claimed
US-5503877-A ORGANONITROGEN, ORGANOMETALLIC POLYMERS OR OLIGOMERS;REDUCTION ATOTECH DEUTSCHALND GMBH (DE) 1996-04-02 US claimed