SCHEMBL4025968

SCHEMBL4025968

CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC(=O)c3cn[nH]c3)c2)C1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A3 P48764 13/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4029734 0.90 SLC9A3 (0.51) SLC9A3
SCHEMBL4026399 0.88 SLC9A3 (0.61) SLC9A3
SCHEMBL4032361 0.87 SLC9A3 (0.57) SLC9A3
SCHEMBL4032420 0.87 SLC9A3 (0.60) SLC9A3
SCHEMBL4025416 0.86 SLC9A3 (0.61) SLC9A3
SCHEMBL4032421 0.85 SLC9A3 (0.60) SLC9A3
SCHEMBL4032773 0.85 SLC9A3 (0.60) SLC9A3
SCHEMBL6500651 0.83 SLC9A3 (0.66) SLC9A3
SCHEMBL4025508 0.83 SLC9A3 (0.68) SLC9A3
SCHEMBL4028711 0.83 SLC9A3 (0.68) SLC9A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453810-B1 SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME SANOFI AVENTIS DEUTSCHLAND (DE) 2009-03-18 EP claimed