⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269786 | 0.76 | — | — | |
| SCHEMBL3396305 | 0.73 | — | — | |
| SCHEMBL3514462 | 0.71 | — | — | |
| SCHEMBL17979575 | 0.71 | NPSR1 (0.38) | — | |
| SCHEMBL4922580 | 0.61 | — | — | |
| SCHEMBL14562887 | 0.60 | — | — | |
| SCHEMBL1930167 | 0.58 | KDM4C (0.53) | — | |
| SCHEMBL4919464 | 0.58 | — | — | |
| SCHEMBL5346431 | 0.58 | — | — | |
| SCHEMBL9587880 | 0.58 | KDM4C (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767528-B1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2014-09-17 | — | — | EP | disclosed |
| US-7488831-B2 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20080200475-A1 | 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors | PFIZER INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1866317-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20070185334-A1 | Process for producing 5-hydroxy-4-thiomethylpyrazole compound | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1767528-A1 | PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006103555-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-0710661-B1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5716958-A | GASTROINTESTINAL DISORDERS; INHIBITORY ACTIVITY ON CHOLECYSTOKININ | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0710661-A1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5470867-A | Imidazoles and their salts having antagonistic activity to angiotesin II recetors | ROUSSEL-UCLAF (FR) | 1995-11-28 | — | — | US | disclosed |
| US-5389634-A | Treating arterial hypertension, relaxing uterus, prevention of post-angioplastic restenosis | ROUSSEL-UCLAF (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5338756-A | Angiotensin II receptor antagonists | ROUSSEL UCLAF (FR) | 1994-08-16 | — | — | US | disclosed |