Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026062 | 1.00 | NPY5R (0.75) | NPY5R | |
| Hydrochloric Acid SCHEMBL4093178 | 0.99 | NPY5R (0.74) | NPY5R | |
| Hydrochloric Acid SCHEMBL4093177 | 0.99 | NPY5R (0.74) | NPY5R | |
| SCHEMBL4020203 | 0.91 | NPY5R (0.79) | NPY5R | |
| SCHEMBL4020205 | 0.91 | NPY5R (0.79) | NPY5R | |
| Hydrochloric Acid SCHEMBL4095969 | 0.90 | NPY5R (0.78) | NPY5R | |
| Hydrochloric Acid SCHEMBL4095974 | 0.90 | NPY5R (0.78) | NPY5R | |
| SCHEMBL4023059 | 0.87 | NPY5R (0.75) | NPY5R | |
| SCHEMBL4023061 | 0.87 | NPY5R (0.75) | NPY5R | |
| Hydrochloric Acid SCHEMBL4099921 | 0.86 | NPY5R (0.74) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203705-A1 | Spiro Compounds As NPY Y5 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| WO-2009095377-A1 | SPIRO COMPOUNDS AS NPY Y5 RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203705-A1 | Spiro Compounds As NPY Y5 Receptor Antagonists | NPY4R, NPY1R, NPY5R | NPY5R 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.