SCHEMBL4026294

SCHEMBL4026294

Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCCNOCCC(=O)OC(C)(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.57
PPARA Q07869 17/20 0.57
PPARD Q03181 8/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4028630 0.88 PPARG (0.57) PPARGPPARAPPARD
SCHEMBL4032153 0.84 PPARG (0.61) PPARGPPARAPPARD
SCHEMBL13721247 0.82 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL13718953 0.81 PPARA (0.64) PPARGPPARAPPARD
SCHEMBL7906850 0.79 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL4035733 0.79 BCHE (0.49)
SCHEMBL7897351 0.78 FFAR1 (0.83) PPARGPPARAPPARD
SCHEMBL7903513 0.77 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL4026004 0.77 PPARG (0.61) PPARGPPARAPPARD
SCHEMBL13718639 0.77 PPARA (0.74) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569916-B1 SUBSTITUTED ARALKYL DERIVATIVES CADILA HEALTHCARE LTD (IN) 2009-01-07 EP claimed