⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753907 | 0.70 | — | — | |
| SCHEMBL14631160 | 0.64 | — | — | |
| SCHEMBL3720483 | 0.64 | — | — | |
| SCHEMBL4446045 | 0.63 | — | — | |
| SCHEMBL3073245 | 0.61 | — | — | |
| SCHEMBL9619300 | 0.60 | — | — | |
| SCHEMBL9569884 | 0.57 | — | — | |
| SCHEMBL991267 | 0.55 | — | — | |
| SCHEMBL28315368 | 0.54 | — | — | |
| SCHEMBL6873550 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851864-B1 | NOVEL COUPLING AGENTS, PROCESSES FOR THEIR PREPARATION AND HAIR DYES | SCHWARZKOPF GMBH HANS (DE) | 2001-05-23 | — | — | EP | claimed |
| EP-0851864-A1 | NOVEL COUPLING AGENTS, PROCESSES FOR THEIR PREPARATION AND HAIR DYES | Hans Schwarzkopf GmbH & Co. KG (DE) | 1998-07-08 | — | — | EP | claimed |
| WO-1997010237-A1 | NOVEL COUPLING AGENTS, PROCESSES FOR THEIR PREPARATION AND HAIR DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1997-03-20 | — | — | WO | claimed |
| CN-116284188-B | Double-substrate inhibitor of DNA methyltransferase DNMT1 and application thereof | 南开大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-114502161-B | Use of heterocyclic derivatives with cardiomyocyte proliferative activity in the treatment of heart diseases | 上海市东方医院（同济大学附属东方医院） | 2024-03-29 | — | — | CN | disclosed |
| CN-116284188-A | Double-substrate inhibitor of DNA methyltransferase DNMT1 and application thereof | 南开大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-110573509-B | MLKL inhibitors | 北京生命科学研究所 | 2023-05-26 | — | — | CN | disclosed |
| CN-114929690-B | Novel heterocyclic derivatives having cardiomyocyte proliferative activity for the treatment of heart disease | 同济大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-114929690-A | Novel heterocyclic derivatives with cardiomyocyte proliferative activity for the treatment of cardiac diseases | 同济大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-108690016-B | Pyrazolopyridines and uses thereof | 广东东阳光药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1997020000-A2 | IMPROVED COLORANT STABILIZERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
| WO-1997010237-A1 | NOVEL COUPLING AGENTS, PROCESSES FOR THEIR PREPARATION AND HAIR DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1997-03-20 | — | — | WO | disclosed |
| US-5599522-A | CONTRAST ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 1997-02-04 | — | — | US | disclosed |
| EP-0515458-B1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI | NYCOMED INNOVATION AB (SE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0515458-A1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI. | HAFSLUND NYCOMED INNOVATION (SE) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012024-A1 | TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI | HAFSLUND NYCOMED INNOVATION AB (SE) | 1991-08-22 | — | — | WO | disclosed |
| EP-0189586-B1 | PROCESS FOR THE PREPARATION OF SALTS OF 1,3-DIOXOLANE-4-CARBOXYLIC ACIDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0189586-A1 | Process for the preparation of salts of 1,3-dioxolane-4-carboxylic acids | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-08-06 | — | — | EP | disclosed |