Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31549875 | 1.00 | TDP1 (0.70) | TDP1MAPTALDH1A1SIRT6PLA2G1B | |
| SCHEMBL23111302 | 0.89 | TDP1 (0.76) | TDP1MAPTALDH1A1SIRT6PLA2G1B | |
| SCHEMBL6552076 | 0.88 | TDP1 (0.64) | TDP1MAPTALDH1A1SIRT6PLA2G1B | |
| SCHEMBL1315721 | 0.87 | TDP1 (0.59) | TDP1MAPTALDH1A1SMN1; SMN2ABL1 | |
| SCHEMBL17530357 | 0.86 | TDP1 (0.76) | TDP1MAPTALDH1A1SIRT6PLA2G1B | |
| SCHEMBL10789757 | 0.84 | TDP1 (0.84) | TDP1MAPTALDH1A1SIRT6KMT2A | |
| SCHEMBL14397211 | 0.84 | ABL1 (0.53) | TDP1MAPTALDH1A1SIRT6PLA2G1B | |
| SCHEMBL1186362 | 0.83 | TDP1 (0.52) | TDP1MAPTALDH1A1PLA2G1BATG4B | |
| SCHEMBL267821 | 0.83 | MAPT (0.65) | TDP1MAPTALDH1A1PLA2G1BATG4B | |
| SCHEMBL28436639 | 0.83 | SMN1; SMN2 (0.60) | TDP1MAPTALDH1A1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813478-B | Method for heterogeneous catalysis of nitroarene reduction by using ultraviolet light driven molybdenum diselenide nano carbon material | 湖南大学 | 2025-04-22 | — | — | CN | claimed |
| CN-119684179-A | Diaryl ether compound and preparation method and application thereof | 沈阳农业大学 | 2025-03-25 | — | — | CN | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118084672-A | Method for preparing 5-chloro-2-nitrobenzoic acid methyl ester by adopting microchannel reactor | 常州大学 | 2024-05-28 | — | — | CN | claimed |
| EP-0080312-B1 | THE PREPARATION OF CERTAIN DIPHENYL ETHERS ESPECIALLY 5-(4-TRIFLUOROMETHYLPHENOXY)- AND 5-(2-HALO-4-TRIFLUOROMETHYLPHENOXY)-2-NITROBENZOIC ACID AND SALTS AND ESTERS AND AMIDES | ROHM AND HAAS COMPANY (US) | 1985-05-29 | — | — | EP | claimed |
| EP-0080312-A1 | The preparation of certain diphenyl ethers especially 5-(4-trifluoromethylphenoxy)- and 5-(2-halo-4-trifluoromethylphenoxy)-2-nitrobenzoic acid and salts and esters and amides | ROHM AND HAAS COMPANY (US) | 1983-06-01 | — | — | EP | claimed |
| US-20250129086-A1 | COMPOUND FOR DEGRADING EGFR PROTEIN AND USE THEREOF | TYK MEDICINES, INC. (CN) | 2025-04-24 | — | — | US | disclosed |
| CN-116813478-B | Method for heterogeneous catalysis of nitroarene reduction by using ultraviolet light driven molybdenum diselenide nano carbon material | 湖南大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-119684179-A | Diaryl ether compound and preparation method and application thereof | 沈阳农业大学 | 2025-03-25 | — | — | CN | disclosed |
| EP-4434978-A1 | COMPOUND FOR DEGRADING EGFR PROTEIN AND USE THEREOF | TYK Medicines Inc. (CN) | 2024-09-25 | — | — | EP | disclosed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118084672-A | Method for preparing 5-chloro-2-nitrobenzoic acid methyl ester by adopting microchannel reactor | 常州大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084672-A | Method for preparing 5-chloro-2-nitrobenzoic acid methyl ester by adopting microchannel reactor | 常州大学 | 2024-05-28 | — | — | CN | disclosed |
| US-4164409-A | Substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof | MOBIL OIL CORP. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4164410-A | Esters of substituted phenoxybenzoic acids, compositions of the same and herbicidal use thereof | MOBIL OIL CORP. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4031131-A | 3-HYDROXYBENZOIC ACID, 3-CHLORO-4-HALOBENZOTRIFLUORIDE | ROHM AND HAAS COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4002662-A | HERBICIDES | MOBIL OIL CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3983168-A | HERBICIDES | MOBIL OIL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3979437-A | HERBICIDES | MOBIL OIL CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3941830-A | HERBICIDE | MOBIL OIL CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129086-A1 | COMPOUND FOR DEGRADING EGFR PROTEIN AND USE THEREOF | EGFR, ERBB2, ERBB4 | TDP1 3553/4885MAPT 3703/4885ALDH1A1 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.