Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | CASP3 | P42574 | 5/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133934 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9152783 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4206081 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4909203 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL8938070 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL31036258 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9151570 | 1.00 | GSK3B (0.38) | GSK3BKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1234203 | 0.98 | GSK3B (0.39) | GSK3BKDM4EALDH1A1GAAHPGD | |
| Phthalimide SCHEMBL8559536 | 0.97 | GSK3B (0.44) | GSK3BKDM4EALDH1A1GAAHPGD | |
| Phthalimide SCHEMBL8558696 | 0.96 | GSK3B (0.43) | GSK3BKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402448-B | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-113402448-A | Terpyridyl primary amine organic corrosion inhibitor and preparation method and application thereof | 中国船舶重工集团公司第七二五研究所 | 2021-09-17 | — | — | CN | disclosed |
| EP-2096107-A1 | Derivatives of squaric acid with anti-proliferative activity | GPC Biotech AG (DE) | 2009-09-02 | — | — | EP | disclosed |
| EP-1674457-B1 | Derivatives of squaric acid with anti-proliferative activity | GPC BIOTECH AG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-1674457-A1 | Derivatives of squaric acid with anti-proliferative activity | GPC Biotech AG (DE) | 2006-06-28 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |