Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021435 | 0.80 | HPGD (0.67) | MAPTKMT2AALDH1A1POLBHPGD | |
| SCHEMBL4925746 | 0.79 | GAA (0.55) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4029707 | 0.76 | POLB (0.51) | RXFP1ALDH1A1POLBKDM4EHPGD | |
| SCHEMBL14409571 | 0.75 | TSHR (0.70) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL6973124 | 0.75 | GAA (0.73) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL4031125 | 0.74 | SMN1; SMN2 (0.55) | RXFP1MAPTKMT2AALDH1A1POLB | |
| SCHEMBL3184163 | 0.73 | HPGD (1.00) | KMT2AALDH1A1POLBHPGDNPC1 | |
| SCHEMBL3204586 | 0.73 | HPGD (0.93) | KMT2AALDH1A1POLBHPGDNPC1 | |
| SCHEMBL314589 | 0.73 | TSHR (0.75) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5721942 | 0.73 | TSHR (0.51) | RXFP1MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |