SCHEMBL4028248

SCHEMBL4028248

Cn1cc(CF)c(OC(=O)Nc2ccccc2-c2cccc(Cl)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 19/20 0.52
CHRM1 P11229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026096 0.89 CHRM3 (0.52) CHRM3
SCHEMBL4026961 0.89 CHRM3 (0.48) CHRM3CHRM1
SCHEMBL4024550 0.88 CHRM3 (0.52) CHRM3CHRM1
SCHEMBL4024233 0.87 CHRM3 (0.52) CHRM3
SCHEMBL4026463 0.85 CHRM3 (0.52) CHRM3CHRM1
SCHEMBL4030244 0.84 CHRM3 (0.46) CHRM3CHRM1
SCHEMBL4025520 0.84 CHRM3 (0.49) CHRM3CHRM1
SCHEMBL4025143 0.83 CHRM3 (0.50) CHRM3
SCHEMBL5142201 0.82 CHRM3 (0.50) CHRM3CHRM1
SCHEMBL4031110 0.82 CHRM3 (0.56) CHRM3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed