SCHEMBL4028287

SCHEMBL4028287

CCCCC(=O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10856092 0.97
SCHEMBL1951862 0.92
Phosphonic Acid SCHEMBL28227163 0.91 HTR2C (0.47)
Hydrochloric Acid SCHEMBL5378829 0.90 HTR2C (0.55)
SCHEMBL14991020 0.90 KMT2A (0.60)
SCHEMBL25234182 0.90 KMT2A (0.60)
SCHEMBL9683681 0.90 KMT2A (0.60)
SCHEMBL5932841 0.90 KMT2A (0.60)
SCHEMBL4578237 0.90 KMT2A (0.60)
SCHEMBL28904119 0.90 KMT2A (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022247065-A1 SYNTHESIS METHOD FOR PENTOXIFYLLINE 海南通用康力制药有限公司 2022-12-01 WO claimed
US-20110054034-A1 METHODS OF USING CARBOXYLIC AMIDES AS ANTIMICROBIAL AGENTS GRAND VALLEY STATE UNIVERSITY 2011-03-03 US claimed
WO-2009100323-A2 METHODS OF USING CARBOXYLIC AMIDES AS ANTIMICROBIAL AGENTS GRAND VALLEY STATE UNIVERSITY (US) 2009-08-13 WO claimed
US-6727250-B2 ADMINISTERING COMPOUNDS SUCH AS TRANS-3-(NAPHTH-2-YL)-BUT-2-ENOIC ACID-N-(2-CARBOXY-PHENYL)-AMIDE OR LIKE FOR THERAPY OF CONDITIONS ASSOCIATED WITH INCREASED TELOMERASE ACTIVITY, E.G. TUMOUR DISEASES BOEHRINGER INGELHEIM PHARMA KG (DE) 2004-04-27 US claimed
US-20020099089-A1 Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-07-25 US claimed
WO-1997049668-A1 INHIBITIORS OF CYSTEINE PROTEASE SMITHKLINE BEECHAM CORPORATION (US) 1997-12-31 WO claimed
EP-0468470-B1 Benzimidazoles, medicaments containing them and process for their preparation THOMAE GMBH DR K (DE) 1997-04-16 EP claimed
US-20250288583-A1 Treatment of Mucus Hypersecretion ALTA RESEARCH, LLC 2025-09-18 US disclosed
US-20230372511-A1 ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-11-23 US disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
US-11717576-B2 Antibody-immune agonist conjugate and applications thereof GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
WO-2022247065-A1 SYNTHESIS METHOD FOR PENTOXIFYLLINE 海南通用康力制药有限公司 2022-12-01 WO disclosed
US-5565469-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1996-10-15 US disclosed
CN-1113235-A Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them THOMAE GMBH DR K (DE) 1995-12-13 CN disclosed
US-5459147-A Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma DR. KARL THOMAE GMBH (DE) 1995-10-17 US disclosed
US-5385925-A Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them DR. KARL THOMAE GMBH (DE) 1995-01-31 US disclosed
CN-1083812-A Benzimidazoles contains the pharmaceutical composition of these compounds and their preparation KRAL THOMAE GMBH (DE) 1994-03-16 CN disclosed
EP-0581166-A1 Benzimidazoles, process for their preparation and their use as angiotensin-II antagonists Dr. Karl Thomae GmbH (DE) 1994-02-02 EP disclosed
US-4065471-A N-(4-Amino-2-butynyl)imides STERLING DRUG INC. (US) 1977-12-27 US disclosed