Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 10/20 | 0.76 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593795 | 0.90 | SMYD2 (0.87) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL3594007 | 0.86 | SMYD2 (1.00) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL3590884 | 0.86 | SMYD2 (1.00) | SMYD2ADRB2DRD2DRD1DRD4 | |
| Trifluoroacetic Acid SCHEMBL3592082 | 0.86 | SMYD2 (0.80) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL17476251 | 0.86 | SMYD2 (1.00) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL17476249 | 0.85 | SMYD2 (1.00) | SMYD2ADRB2DRD2DRD1DRD4 | |
| Trifluoroacetic Acid SCHEMBL3605825 | 0.83 | SMYD2 (0.91) | SMYD2ADRB2DRD2DRD1DRD4 | |
| Trifluoroacetic Acid SCHEMBL3599481 | 0.83 | SMYD2 (0.91) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL3606169 | 0.82 | SMYD2 (0.85) | SMYD2ADRB2DRD2DRD1DRD4 | |
| SCHEMBL3598223 | 0.82 | SMYD2 (0.85) | SMYD2ADRB2DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094646-A1 | AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES | AstraZeneca AB (SE) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008075025-A1 | AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |