Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654346 | 0.94 | TSHR (0.37) | TSHR | |
| SCHEMBL22401690 | 0.87 | TSHR (0.41) | TSHR | |
| SCHEMBL4619281 | 0.73 | — | — | |
| SCHEMBL4618906 | 0.73 | — | — | |
| SCHEMBL4655171 | 0.71 | TSHR (0.39) | TSHR | |
| SCHEMBL33924 | 0.71 | — | — | |
| SCHEMBL4823214 | 0.71 | — | — | |
| SCHEMBL23322351 | 0.71 | — | — | |
| SCHEMBL21232965 | 0.71 | — | — | |
| SCHEMBL3633808 | 0.71 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101774-B2 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-6495643-B1 | RING OPENING POLYMERIZATION OF SUCH AS 6-METHYLENE-1,4-DITHIEPANE OPTIONALLY WITH METHYL METHACRYLATE; MINIMIZING SHRINKAGE; HIGH MOLECULAR WEIGHT; SUCH AS AMIDE, ESTER OR CARBONATE BACKBONE GROUPS; ADHESIVES, COMPOSITES, LENSES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2002-12-17 | — | — | US | disclosed |