Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 8/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypochlorous Acid SCHEMBL4102672 | 0.97 | MAPT (0.48) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL4200420 | 0.90 | MAPT (0.48) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hypochlorous Acid SCHEMBL4110353 | 0.88 | MAPT (0.46) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL4210830 | 0.87 | MAPT (0.50) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hypochlorous Acid SCHEMBL4116052 | 0.84 | MAPT (0.48) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hypochlorous Acid SCHEMBL4110717 | 0.81 | MAPT (0.47) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hydrochloric Acid SCHEMBL4113957 | 0.79 | MAPT (0.58) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hypochlorous Acid SCHEMBL4113963 | 0.78 | MAPT (0.57) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL13649303 | 0.77 | MAPT (0.49) | MAPTALDH1A1LMNAHTTKDM4E | |
| Hypochlorous Acid SCHEMBL4115442 | 0.76 | MAPT (0.48) | MAPTALDH1A1LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010481-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | Fluofarma (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007125196-A1 | TYPE 1, 4-NAPHTOQUINONE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USE OF THESE COMPOUNDS AS ANTI-CANCER AGENTS | FLUOFARMA (FR) | 2007-11-08 | — | — | WO | disclosed |