Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027890 | 0.91 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL4031612 | 0.91 | SLC9A3 (0.50) | SLC9A3 | |
| SCHEMBL4034181 | 0.90 | SLC9A3 (0.49) | SLC9A3NPC1RAB9A | |
| SCHEMBL4026500 | 0.90 | SLC9A3 (0.61) | SLC9A3NPC1RAB9A | |
| SCHEMBL4028653 | 0.89 | SLC9A3 (0.46) | SLC9A3 | |
| SCHEMBL4027757 | 0.86 | SLC9A3 (0.48) | SLC9A3 | |
| SCHEMBL4028650 | 0.86 | SLC9A3 (0.50) | SLC9A3 | |
| SCHEMBL4031999 | 0.84 | SLC9A3 (0.45) | SLC9A3RAB9A | |
| SCHEMBL2576031 | 0.84 | SLC9A3 (0.54) | SLC9A3 | |
| SCHEMBL4031638 | 0.84 | SLC9A3 (0.56) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1453810-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AS MEDICAMENTS, IN ADDITION TO A MEDICAMENT CONTAINING SAME | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-03-18 | — | — | EP | disclosed |