Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 15/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030658 | 1.00 | BDKRB1 (0.54) | BDKRB1NISCHMEN1NPC1TSHR | |
| SCHEMBL4030386 | 0.91 | BDKRB1 (0.59) | BDKRB1NISCH | |
| SCHEMBL4030385 | 0.91 | BDKRB1 (0.59) | BDKRB1NISCH | |
| SCHEMBL4033078 | 0.88 | BDKRB1 (0.58) | BDKRB1NISCHKMT2A | |
| SCHEMBL4033075 | 0.88 | BDKRB1 (0.58) | BDKRB1NISCHKMT2A | |
| SCHEMBL4030692 | 0.88 | BDKRB1 (0.59) | BDKRB1KMT2A | |
| SCHEMBL4030698 | 0.88 | BDKRB1 (0.59) | BDKRB1KMT2A | |
| SCHEMBL4030656 | 0.87 | BDKRB1 (0.69) | BDKRB1NISCHMEN1NPC1TSHR | |
| SCHEMBL5118019 | 0.87 | BDKRB1 (0.69) | BDKRB1NISCHMEN1NPC1TSHR | |
| SCHEMBL4204340 | 0.85 | BDKRB1 (0.49) | BDKRB1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521744-B1 | ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS B1 BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER LAB SA (FR) | 2009-04-01 | — | — | EP | disclosed |
| EP-1521744-A1 | ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS B1 BRADYKININ RECEPTOR ANTAGONISTS | LABORATOIRES FOURNIER S.A. (FR) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003106428-A1 | NOVEL ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS THERAPEUTIC AGENTS | LABORATOIRES FOURNIER SA (FR) | 2003-12-24 | — | — | WO | disclosed |