Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 18/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084799 | 1.00 | CXCR4 (0.44) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2084800 | 1.00 | CXCR4 (0.44) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2084796 | 1.00 | CXCR4 (0.44) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2084324 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2084325 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL23428716 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2083850 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL12935741 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2083848 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB | |
| SCHEMBL2083846 | 0.94 | CXCR4 (0.50) | CXCR4MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |