Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 15/20 | 0.58 |
| ▸ | PPARA | Q07869 | 15/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034346 | 0.96 | FFAR1 (0.66) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4035144 | 0.91 | KDR (0.67) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4032164 | 0.90 | FFAR1 (0.76) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4029476 | 0.90 | KDR (0.67) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4032526 | 0.89 | KDR (0.69) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL4030470 | 0.88 | KDR (0.70) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4035383 | 0.88 | FFAR1 (0.60) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5403576 | 0.88 | FFAR1 (0.79) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4029683 | 0.86 | KDR (0.70) | FFAR1PPARGPPARAKDRKDM4E | |
| SCHEMBL4033666 | 0.86 | FFAR1 (0.55) | FFAR1PPARGPPARAKDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-7238716-B2 | Alkanoic acid derivatives process for their production and use thereof | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |