SCHEMBL4030874

SCHEMBL4030874

[CH2][C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)OCC

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.66
PPARA Q07869 14/20 0.65
PPARD Q03181 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4027819 0.87 PPARG (0.65) PPARGPPARAPPARD
SCHEMBL4025861 0.87 PPARG (0.65) PPARGPPARAPPARD
SCHEMBL4032154 0.86 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL10211509 0.86 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL13633933 0.85 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL4031992 0.85 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL4027274 0.85 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL6201076 0.85 PPARG (0.65) PPARGPPARAPPARD
SCHEMBL4026882 0.84 PPARG (0.62) PPARGPPARAPPARD
SCHEMBL4516217 0.84 PPARG (0.62) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569916-B1 SUBSTITUTED ARALKYL DERIVATIVES CADILA HEALTHCARE LTD (IN) 2009-01-07 EP claimed